NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
Raising cellular levels of the metabolic cofactor NAD+ reverses key indicators of aging. Here, Ratajczak et al. show that cellular levels of NAD+ depend on the extracellular catalytic activity of NRK1, which processes two NAD+precursors, nicotinamide mononucleotide and nicotinamide riboside, in mice...
שמור ב:
| Principais autores: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Portfolio
2016-10-01
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| סדרה: | Nature Communications |
| גישה מקוונת: | https://doi.org/10.1038/ncomms13103 |
| תגים: |
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