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Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

Abstract Background β-Nicotinamide mononucleotide (NMN) is the direct precursor of nicotinamide coenzymes such as NAD+ and NADP+, which are widely applied in industrial biocatalysis especially involving cofactor-dependent oxidoreductases. Moreover, NMN is a promising candidate for medical uses since...

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Principais autores: Xiao-Long Qian, Yi-Si Dai, Chun-Xiu Li, Jiang Pan, Jian-He Xu, Bozhong Mu
Formato: Artigo
Idioma:Inglês
Publicado: SpringerOpen 2022-03-01
Series:Bioresources and Bioprocessing
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Acceso en liña:https://doi.org/10.1186/s40643-022-00514-6
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