Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors

Increased interstitial fluid pressure (IFP) in brain tumors results in rapid removal of drugs from tumor extracellular space. We studied the effects of dexamethasone and hypothermia on IFP in s.c. RG-2 rat gliomas, because they could potentially be useful as means of maintaining drug concentrations...

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Détails bibliographiques
Auteurs principaux: Navalitloha, Yot, Schwartz, Erica S., Groothuis, Elizabeth N., Allen, Cathleen V., Levy, Robert M., Groothuis, Dennis R.
Format: Artigo
Langue:Inglês
Publié: Duke University Press 2006
Sujets:
Basic and Translational Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871948/
https://ncbi.nlm.nih.gov/pubmed/16775223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-007
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