Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors

Increased interstitial fluid pressure (IFP) in brain tumors results in rapid removal of drugs from tumor extracellular space. We studied the effects of dexamethasone and hypothermia on IFP in s.c. RG-2 rat gliomas, because they could potentially be useful as means of maintaining drug concentrations...

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Autori principali: Navalitloha, Yot, Schwartz, Erica S., Groothuis, Elizabeth N., Allen, Cathleen V., Levy, Robert M., Groothuis, Dennis R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Duke University Press 2006
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871948/
https://ncbi.nlm.nih.gov/pubmed/16775223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-007
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