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Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors

Increased interstitial fluid pressure (IFP) in brain tumors results in rapid removal of drugs from tumor extracellular space. We studied the effects of dexamethasone and hypothermia on IFP in s.c. RG-2 rat gliomas, because they could potentially be useful as means of maintaining drug concentrations...

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Detalhes bibliográficos
Main Authors: Navalitloha, Yot, Schwartz, Erica S., Groothuis, Elizabeth N., Allen, Cathleen V., Levy, Robert M., Groothuis, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871948/
https://ncbi.nlm.nih.gov/pubmed/16775223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-007
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