Comparative pharmacokinetics of (14)C-sucrose in RG-2 rat gliomas after intravenous and convection-enhanced delivery

We compared tissue and plasma pharmacokinetics of (14)C-sucrose in subcutaneous RG-2 rat gliomas after administration by 3 routes, intravenous bolus (IV-B; 50 μCi over 30 s), continuous IV infusion (IV-C, 50 μCi at a constant rate), and convection-enhanced delivery (CED, 5 μCi infused at a rate of 0...

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Detalhes bibliográficos
Main Authors: Vavra, Michael, Ali, M. Jaffer, Kang, Eric W.-Y., Navalitloha, Yot, Ebert, Allison, Allen, Cathleen V., Groothuis, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2004
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871980/
https://ncbi.nlm.nih.gov/pubmed/15134624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851703000449
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