Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo

U87MG human glioma cells in cultures expressed metabotropic glutamate (mGlu) receptors mGlu2 and mGlu3. Addition of the mGlu2/3 receptor antagonist LY341495 to the cultures reduced cell growth, expression of cyclin D1/2, and activation of the MAP kinase and phosphatidylinositol-3-kinase pathways. Th...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Arcella, Antonietta, Carpinelli, Giulia, Battaglia, Giuseppe, D’Onofrio, Mara, Santoro, Filippo, Ngomba, Richard Teke, Bruno, Valeria, Casolini, Paola, Giangaspero, Felice, Nicoletti, Ferdinando
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Duke University Press 2005
Onderwerpen:
Basic and Translational Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871912/
https://ncbi.nlm.nih.gov/pubmed/16053698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704000961
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items