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Interferon γ-producing γδ T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection

Ig class switching usually occurs as a consequence of cognate interactions between antigen-specific B cells and CD4(+) αβ T cells. Vesicular stomatitis virus (VSV) infection of immunocompetent mice induces a rapid T-independent neutralizing IgM response followed by a long-lived T-dependent IgG respo...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Maloy, Kevin J., Odermatt, Bernhard, Hengartner, Hans, Zinkernagel, Rolf M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1160
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