Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death

Centromere protein C (CENPC) is a key protein that has been localized to the inner kinetochore plate of active mammalian centromeres. Using gene targeting techniques, we have disrupted the mouse Cenpc gene and shown that the gene is essential for normal mouse embryonic development. Heterozygous mice...

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Xehetasun bibliografikoak

Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Kalitsis, Paul, Fowler, Kerry J., Earle, Elizabeth, Hill, Joanne, Choo, K. H. Andy
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1998
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1136
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