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Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma.

To understand the role of urokinase (u-PA) and the urokinase receptor (u-PAR) in malignant astrocytoma cell invasion of normal brain, astrocytic expression of u-PAR and u-PA mRNAs were analyzed by riboprobe in situ hybridization in astrocytoma and non-neoplastic brain biopsies. In eight of eight mal...

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Bibliographic Details
Main Authors: Gladson, C. L., Pijuan-Thompson, V., Olman, M. A., Gillespie, G. Y., Yacoub, I. Z.
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869284/
https://ncbi.nlm.nih.gov/pubmed/7747809
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