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Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas.

Pilocytic astrocytomas of the optic nerve (optic nerve gliomas) are closely associated with neurofibromatosis 1 (NF1), and allelic losses of the NF1 gene region on chromosome 17q occur in sporadic pilocytic astrocytomas. We therefore hypothesized that the NF1 gene acts as a tumor suppressor gene in...

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Bibliografski detalji
Glavni autori: Platten, M., Giordano, M. J., Dirven, C. M., Gutmann, D. H., Louis, D. N.
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865298/
https://ncbi.nlm.nih.gov/pubmed/8702000
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