Role of the p110δ PI 3-kinase in integrin and ITAM receptor signalling in platelets

We have investigated the function of the p110δ catalytic subunit of phosphoinositide 3-kinase (PI 3-kinase) in platelets using p110δ knockout (p110δ(-/-)) mice and p110δ knock-in (p110δ(D910A/D910A)) mice, which express a catalytically inactive form of the enzyme. Aggregation to threshold concentrat...

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Hlavní autoři: Senis, Yotis A., Atkinson, Ben T., Pearce, Andrew C., Wonerow, Peter, Auger, Jocelyn M., Okkenhaug, Klaus, Pearce, Wayne, Vigorito, Elena, Vanhaesebroeck, Bart, Turner, Martin, Watson, Steve P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868960/
https://ncbi.nlm.nih.gov/pubmed/16011964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537100400016711
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