HER2 therapy. Small molecule HER-2 tyrosine kinase inhibitors

Overexpression of the human epidermal growth factor receptor (HER)-2 oncogenic receptor tyrosine kinase, which occurs in 25% of breast cancers, portends poor clinical outcome and consequently represents an attractive target for therapeutic intervention. Small molecule tyrosine kinase inhibitors that...

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Bibliografiska uppgifter
Huvudupphovsmän: Spector, Neil, Xia, Wenle, El-Hariry, Iman, Yarden, Yossi, Bacus, Sarah
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868927/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1652
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