Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors

BACKGROUND: Monocyte-derived-dendritic-cells (MDDC) are the major DC type used in vaccine-based clinical studies for a variety of cancers. In order to assess whether in vitro differentiated MDDC from cryopreserved PBMC of cancer patients are functionally distinct from those of healthy donors, we com...

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Detalhes bibliográficos
Main Authors: Ghanekar, Smita A, Bhatia, Sonny, Ruitenberg, Joyce J, Rosa, Corazon DeLa, Disis, Mary L, Maino, Vernon C, Maecker, Holden T, Waters, Cory A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868730/
https://ncbi.nlm.nih.gov/pubmed/17477875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-5-7
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