Immunohistochemical Labeling for Dpc4 Mirrors Genetic Status in Pancreatic Adenocarcinomas : A New Marker of DPC4 Inactivation

DPC4 (MADH4, SMAD4) is a tumor suppressor gene inactivated by allelic loss in approximately 55% of pancreatic adenocarcinomas. Unfortunately, it can be technically very difficult to detect the inactivation of DPC4 at the genetic level because genetic analyses require the microdissection of relativel...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wilentz, Robb E., Su, Gloria H., Dai, Jia Le, Sparks, Andrew B., Argani, Pedram, Sohn, Taylor A., Yeo, Charles J., Kern, Scott E., Hruban, Ralph H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2000
Matèries:
Short Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868651/
https://ncbi.nlm.nih.gov/pubmed/10623651
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars