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Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation

Medulloblastoma, the most common malignant brain tumor of childhood, is believed to derive from immature granule neuron precursors (GNPs) that normally proliferate in the external granule layer before exiting the cell cycle and migrating to their mature location in the inner granule layer. In this s...

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Autors principals: Pogoriler, Jennifer, Millen, Kathleen, Utset, Manuel, Du, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868525/
https://ncbi.nlm.nih.gov/pubmed/16943274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02556
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