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Loss of Smarc Proteins Impairs Cerebellar Development

SMARCA4 (BRG1) and SMARCB1 (INI1) are tumor suppressor genes that are crucially involved in the formation of malignant rhabdoid tumors, such as atypical teratoid/rhabdoid tumor (AT/RT). AT/RTs typically affect infants and occur at various sites of the CNS with a particular frequency in the cerebellu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Moreno, Natalia, Schmidt, Christin, Ahlfeld, Julia, Pöschl, Julia, Dittmar, Stefanie, Pfister, Stefan M., Kool, Marcel, Kerl, Kornelius, Schüller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608313/
https://ncbi.nlm.nih.gov/pubmed/25274825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2560-14.2014
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