ATRT-07. MURINE SOX2-POSITIVE EARLY PRECURSOR CELLS GIVE RISE TO RHABDOID TUMORS WITH FEATURES OF THE HUMAN ATRT-MYC GROUP

PURPOSE: Atypical teratoid rhabdoid tumors (ATRT), characterized by SMARCB1 loss, have been classified by DNA methylation and gene expression profiling into three distinct molecular subgroups (ATRT-SHH, -MYC, -TYR). We hypothesize that ATRT from distinct subgroups have a different cell of origin. ME...

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Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Galarza, Natalia Moreno, Holdhof, Dörthe, Interlandi, Marta, Melcher, Viktoria, Graf, Monika, Kastrati, Dennis, Meisterernst, Michael, Johann, Pascal, Kool, Marcel, Frühwald, Michael, Schüller, Ulrich, Kerl, Kornelius
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012262/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.006
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