ATRT-13. DIFFERENT CELLS OF ORIGIN PAVE THE WAY FOR MOLECULAR HETEROGENEITY IN RHABDOID TUMORS

Rhabdoid tumors (RT) are rare but highly aggressive pediatric neoplasms. These tumors carry homozygous loss-of-function alterations of SMARCB1 in almost all cases with an otherwise low mutational load. RT arise at different intracranial (ATRT) as well as extracranial (MRT) anatomical sites. Three ma...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Graf, Monika, Interlandi, Marta, Moreno, Natalia, Holdhof, Dörthe, Melcher, Viktoria, Kastrati, Dennis, zu Hörste, Gerd Meyer, Dugas, Martin, Frühwald, Michael C, Albert, Thomas K, Schüller, Ulrich, Kerl, Kornelius
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Atypical Teratoid/Rhabdoid Tumors
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715320/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.012
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