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Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias

The basis for mutations at A:T base pairs in immunoglobulin hypermutation and defining how AID interacts with the DNA of the immunoglobulin locus are major aspects of the immunoglobulin mutator mechanism where questions remain unanswered. Here, we examined the pattern of mutations generated in mice...

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Autors principals: Xiao, Zheng, Ray, Madhumita, Jiang, Chuancang, Clark, Alan B., Rogozin, Igor B., Diaz, Marilyn
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868521/
https://ncbi.nlm.nih.gov/pubmed/17240451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.12.006
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