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Ubiquitination of RIP1 regulates an NF-κB-independent cell death switch in TNF signaling

TNF receptor 1 (TNFR1) can trigger opposing responses within the same cell: one leads to a pro-survival response whereas the other leads to cell death [1, 2]. The pro-survival response is mediated primarily by activation of the NF-κB signaling pathway, which leads to the expression of pro-survival g...

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Detalhes bibliográficos
Main Authors: O’Donnell, Marie Anne, Legarda-Addison, Diana, Skountzos, Penelopi, Yeh, Wen Chen, Ting, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868513/
https://ncbi.nlm.nih.gov/pubmed/17306544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.01.027
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