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Development of a Novel Therapeutic Suppressor of Brain Proinflammatory Cytokine Up-Regulation That Attenuates Synaptic Dysfunction and Behavioral Deficits
We report the development of a novel, aqueous-soluble, safe, small molecule, experimental therapeutic that suppresses injury-induced, proinflammatory cytokine increases in the brain, with resultant attenuation of synaptic protein biomarker loss and improvement in hippocampus-dependent behavioral def...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868432/ https://ncbi.nlm.nih.gov/pubmed/17079143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.10.028 |
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