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Adjuvant-enhanced antibody responses occur without Toll-like receptor signaling
Toll-like receptors (TLRs) have been thought to mediate the antibody-enhancing effects of adjuvants. However, we find here that Myd88(−/−); Trif(Lps2/Lps2) mice, which cannot transmit signals through TLRs, mount robust antibody responses to T cell dependent antigen given in four typical adjuvants: a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868398/ https://ncbi.nlm.nih.gov/pubmed/17185603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1135299 |
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