BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) Mutations in Distinct Subsets of Pancreatic Cancer: Potential Therapeutic Targets

The recognition of biologically distinct tumor subsets is fundamental to understanding tumorigenesis. This study investigated the mutational status of the serine/threonine kinase BRAF and the cyclin E regulator FBXW7 (CDC4, FBW7, AGO, SEL10) related to two distinct pancreatic carcinoma subsets: the...

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Main Authors: Calhoun, Eric S., Jones, Jessa B., Ashfaq, Raheela, Adsay, Volkan, Baker, Suzanne J., Valentine, Virginia, Hempen, Paula M., Hilgers, Werner, Yeo, Charles J., Hruban, Ralph H., Kern, Scott E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2003
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868306/
https://ncbi.nlm.nih.gov/pubmed/14507635
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