Proteasome Inhibitor (MG-132) Treatment of mdx Mice Rescues the Expression and Membrane Localization of Dystrophin and Dystrophin-Associated Proteins

Dystrophin, the protein product of the Duchenne muscular dystrophy (DMD) gene, is absent in the skeletal muscle of DMD patients and mdx mice. At the plasma membrane of skeletal muscle fibers, dystrophin associates with a multimeric protein complex, termed the dystrophin-glycoprotein complex (DGC). P...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bonuccelli, Gloria, Sotgia, Federica, Schubert, William, Park, David S., Frank, Philippe G., Woodman, Scott E., Insabato, Luigi, Cammer, Michael, Minetti, Carlo, Lisanti, Michael P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2003
Gaiak:
Animal Model
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868305/
https://ncbi.nlm.nih.gov/pubmed/14507673
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak