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Hypoxia-Induced Gene Expression in Human Macrophages: Implications for Ischemic Tissues and Hypoxia-Regulated Gene Therapy

Macrophages accumulate in ischemic areas of such pathological tissues as solid tumors, atherosclerotic plaques and arthritic joints. Studies have suggested that hypoxia alters the phenotype of macrophages in a way that promotes these lesions. However, the genes up-regulated by macrophages in such hy...

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Autores principales: Burke, Bernard, Giannoudis, Athina, Corke, Kevin P., Gill, Dalvir, Wells, Michael, Ziegler-Heitbrock, Loems, Lewis, Claire E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868302/
https://ncbi.nlm.nih.gov/pubmed/14507633
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