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Hypoxia-Induced Gene Expression in Human Macrophages: Implications for Ischemic Tissues and Hypoxia-Regulated Gene Therapy

Macrophages accumulate in ischemic areas of such pathological tissues as solid tumors, atherosclerotic plaques and arthritic joints. Studies have suggested that hypoxia alters the phenotype of macrophages in a way that promotes these lesions. However, the genes up-regulated by macrophages in such hy...

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Detalhes bibliográficos
Main Authors: Burke, Bernard, Giannoudis, Athina, Corke, Kevin P., Gill, Dalvir, Wells, Michael, Ziegler-Heitbrock, Loems, Lewis, Claire E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868302/
https://ncbi.nlm.nih.gov/pubmed/14507633
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