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Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages

Hypoxia is a hallmark of many pathological tissues. Macrophages accumulate in hypoxic sites and up-regulate a range of hypoxia-inducible genes. The matrix proteoglycan versican has been identified as one such gene, but the mechanisms responsible for hypoxic induction are not fully characterised. Her...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sotoodehnejadnematalahi, Fattah, Staples, Karl J., Chrysanthou, Elvina, Pearson, Helen, Ziegler-Heitbrock, Loems, Burke, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461269/
https://ncbi.nlm.nih.gov/pubmed/26057378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125799
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