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Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation

Aberrant hypermethylation of promoter CpG islands is an important mechanism for the inactivation of tumor suppressor genes. CpG island hypermethylation occurs in relation to tumorigenesis or aging. Gastric cancer is one of the tumors with a high level of aberrant CpG island methylation. However, the...

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Detalhes bibliográficos
Main Authors: Kang, Gyeong Hoon, Lee, Hyeon Joo, Hwang, Kyu Sang, Lee, Sun, Kim, Jae-Hoon, Kim, Jung-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868290/
https://ncbi.nlm.nih.gov/pubmed/14507661
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