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Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation

Aberrant hypermethylation of promoter CpG islands is an important mechanism for the inactivation of tumor suppressor genes. CpG island hypermethylation occurs in relation to tumorigenesis or aging. Gastric cancer is one of the tumors with a high level of aberrant CpG island methylation. However, the...

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Auteurs principaux: Kang, Gyeong Hoon, Lee, Hyeon Joo, Hwang, Kyu Sang, Lee, Sun, Kim, Jae-Hoon, Kim, Jung-Sun
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868290/
https://ncbi.nlm.nih.gov/pubmed/14507661
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