Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells

Since ovarian carcinoma cells detach from the primary lesion and metastasize via peritoneal dissemination, we hypothesized that these cells are exposed to hypoxia, which may affect cell attachment and invasiveness. To address this hypothesis, we first examined in vivo the immunohistochemical express...

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Autores principales: Imai, Tsutomu, Horiuchi, Akiko, Wang, Cuiju, Oka, Kenji, Ohira, Satoshi, Nikaido, Toshio, Konishi, Ikuo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868286/
https://ncbi.nlm.nih.gov/pubmed/14507651
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