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Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells

Since ovarian carcinoma cells detach from the primary lesion and metastasize via peritoneal dissemination, we hypothesized that these cells are exposed to hypoxia, which may affect cell attachment and invasiveness. To address this hypothesis, we first examined in vivo the immunohistochemical express...

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Detalhes bibliográficos
Main Authors: Imai, Tsutomu, Horiuchi, Akiko, Wang, Cuiju, Oka, Kenji, Ohira, Satoshi, Nikaido, Toshio, Konishi, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868286/
https://ncbi.nlm.nih.gov/pubmed/14507651
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