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Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin

Although overexpression of cyclin A2 is reportedly an indicator of a poor prognosis of various malignancies including endometrial carcinoma, its molecular mechanism remains undetermined. To address this issue, we examined the effect of cyclin A2 on the development of resistance to chemotherapeutic d...

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Detalhes bibliográficos
Main Authors: Suzuki, Akihisa, Horiuchi, Akiko, Ashida, Takashi, Miyamoto, Tsutomu, Kashima, Hiroyasu, Nikaido, Toshio, Konishi, Ikuo, Shiozawa, Tanri
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822571/
https://ncbi.nlm.nih.gov/pubmed/19583808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00839.x
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