Co-Expression of p16(INK4A) and Laminin 5 γ2 by Microinvasive and Superficial Squamous Cell Carcinomas in Vivo and by Migrating Wound and Senescent Keratinocytes in Culture

The high frequency of mutation, deletion, and promoter silencing of the gene encoding p16(INK4A) (p16) in premalignant dysplasias and squamous cell carcinomas (SCC) of epidermis and oral epithelium classifies p16 as a tumor suppressor. However, the point during neoplastic progression at which this p...

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Autores principales: Natarajan, Easwar, Saeb, Marcela, Crum, Christopher P., Woo, Sook B., McKee, Phillip H., Rheinwald, James G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868206/
https://ncbi.nlm.nih.gov/pubmed/12875969
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