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Up-Regulation of Phosphorylated/Activated p70 S6 Kinase and Its Relationship to Neurofibrillary Pathology in Alzheimer’s Disease

The ribosomal S6 protein kinase p70 S6 kinase is known for its role in modulating cell-cycle progression, cell size, and cell survival. In response to mitogen stimulation, p70 S6 kinase activation up-regulates ribosomal biosynthesis and enhances the translational capacity of the cell. In Alzheimer’s...

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Bibliografiset tiedot
Päätekijät: An, Wen-Lin, Cowburn, Richard F., Li, Lin, Braak, Heiko, Alafuzoff, Irina, Iqbal, Khalid, Iqbal, Inge-Grundke, Winblad, Bengt, Pei, Jin-Jing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868198/
https://ncbi.nlm.nih.gov/pubmed/12875979
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