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Matrilysin (Matrix Metalloproteinase-7) Mediates E-Cadherin Ectodomain Shedding in Injured Lung Epithelium

Matrilysin (matrix metalloproteinase-7) is highly expressed in lungs of patients with pulmonary fibrosis and other conditions associated with airway and alveolar injury. Although matrilysin is required for closure of epithelial wounds ex vivo, the mechanism of its action in repair is unknown. We dem...

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Autores principales: McGuire, John K., Li, Qinglang, Parks, William C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868120/
https://ncbi.nlm.nih.gov/pubmed/12759241
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