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Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients

Matrilysin [matrix metalloproteinase 7 (MMP7)] is induced by mucosal injury of many tissues. To assess function of this proteinase, we subjected wild-type and Mmp7(−/−) mice to acute colon injury. When matrilysin expression was increasing, 73% of wild-type mice died, whereas only 32% of Mmp7(−/−) mi...

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Библиографические подробности
Главные авторы: Swee, Mei, Wilson, Carole L., Wang, Ying, McGuire, John K., Parks, William C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139120/
https://ncbi.nlm.nih.gov/pubmed/18334539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0108016
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