Association of Platelet-Derived Growth Factor Receptor α Mutations with Gastric Primary Site and Epithelioid or Mixed Cell Morphology in Gastrointestinal Stromal Tumors

Most gastrointestinal stromal tumors (GISTs) carry activating mutations of the KIT gene encoding the receptor tyrosine kinase KIT. In a previous study we were able to show an association between the lack of KIT mutations (wild-type GISTs) and the presence of a significant epithelioid tumor component...

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Main Authors: Wardelmann, Eva, Hrychyk, Aksana, Merkelbach-Bruse, Sabine, Pauls, Katharina, Goldstein, Jennifer, Hohenberger, Peter, Losen, Inge, Manegold, Christoph, Büttner, Reinhard, Pietsch, Torsten
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867629/
https://ncbi.nlm.nih.gov/pubmed/15269295
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