Association of Platelet-Derived Growth Factor Receptor α Mutations with Gastric Primary Site and Epithelioid or Mixed Cell Morphology in Gastrointestinal Stromal Tumors

Most gastrointestinal stromal tumors (GISTs) carry activating mutations of the KIT gene encoding the receptor tyrosine kinase KIT. In a previous study we were able to show an association between the lack of KIT mutations (wild-type GISTs) and the presence of a significant epithelioid tumor component...

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Detalhes bibliográficos
Main Authors: Wardelmann, Eva, Hrychyk, Aksana, Merkelbach-Bruse, Sabine, Pauls, Katharina, Goldstein, Jennifer, Hohenberger, Peter, Losen, Inge, Manegold, Christoph, Büttner, Reinhard, Pietsch, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867629/
https://ncbi.nlm.nih.gov/pubmed/15269295
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