Multiplex Pyrosequencing of Two Polymorphisms in DNA Repair Gene XRCC1

DNA repair enzymes play a pivotal role in platinum-based chemotherapy. Within the gene encoding for the base excision repair enzyme XRCC1, several nonsynonymous polymorphisms have been identified. It has been shown that the Arg399Gln single-nucleotide polymorphism results in a polymorphic enzyme tha...

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Detalles Bibliográficos
Autores principales: van der Straaten, Tahar, Kweekel, Dinemarie, Tiller, Marco, Bogaartz, Judith, Guchelaar, Henk-Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2006
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867628/
https://ncbi.nlm.nih.gov/pubmed/16931584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060018
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