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Multiplex Pyrosequencing of Two Polymorphisms in DNA Repair Gene XRCC1
DNA repair enzymes play a pivotal role in platinum-based chemotherapy. Within the gene encoding for the base excision repair enzyme XRCC1, several nonsynonymous polymorphisms have been identified. It has been shown that the Arg399Gln single-nucleotide polymorphism results in a polymorphic enzyme tha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1867628/ https://ncbi.nlm.nih.gov/pubmed/16931584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060018 |
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