KIT Gene Deletions at the Intron 10−Exon 11 Boundary in GI Stromal Tumors

Most gastrointestinal stromal tumors (GISTs) harbor oncogenic mutations in the KIT gene, and the majority of these mutations affect the juxtamembrane domain of the kinase encoded by exon 11. Screening GISTs for KIT gene mutations is important for translational research studies and for providing prog...

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Autores principales: Corless, Christopher L., McGreevey, Laura, Town, Ajia, Schroeder, Arin, Bainbridge, Troy, Harrell, Patina, Fletcher, Jonathan A., Heinrich, Michael C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2004
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867487/
https://ncbi.nlm.nih.gov/pubmed/15507676
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