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Hyperosmotic Stress Induces Nuclear Factor-κB Activation and Interleukin-8 Production in Human Intestinal Epithelial Cells

Inflammatory bowel disease of the colon is associated with a high osmolarity of colonic contents. We hypothesized that this hyperosmolarity may contribute to colonic inflammation by stimulating the proinflammatory activity of intestinal epithelial cells (IECs). The human IEC lines HT-29 and Caco-2 w...

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Bibliografiske detaljer
Main Authors: Németh, Zoltán H., Deitch, Edwin A., Szabó, Csaba, Haskó, György
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867255/
https://ncbi.nlm.nih.gov/pubmed/12213727
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