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Modulation by dantrolene of endotoxin-induced interleukin-10, tumour necrosis factor-α and nitric oxide production in vivo and in vitro

1. Intracellular calcium has been suggested to be an important mediator of the cellular response in endotoxaemia and shock. Dantrolene is an agent that interferes with intracellular calcium fluxes resulting in a decreased availability of calcium in the cytoplasm. Here we have investigated the effect...

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Autors principals: Haskó, György, Szabó, Csaba, Németh, Zoltán H, Lendvai, Balázs, Vizi, E Sylvester
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565490/
https://ncbi.nlm.nih.gov/pubmed/9720779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701934
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