Cervical Epithelial Cells Transduced with the Papillomavirus E6/E7 Oncogenes Maintain Stable Levels of Oncoprotein Expression but Exhibit Progressive, Major Increases in hTERT Gene Expression and Telomerase Activity

Cervical carcinoma cells display high telomerase activity and usually contain and express integrated copies of the human papillomavirus (HPV) genome. Recent studies have demonstrated that the E6 oncogene of malignancy-associated HPVs increases cellular telomerase activity, predominantly via transcri...

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Detalhes bibliográficos
Main Authors: Baege, Astrid C., Berger, Allison, Schlegel, Robert, Veldman, Tim, Schlegel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867234/
https://ncbi.nlm.nih.gov/pubmed/11943710
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