Induction of Myocarditis and Valvulitis in Lewis Rats by Different Epitopes of Cardiac Myosin and Its Implications in Rheumatic Carditis

Immune responses against cardiac myosin and group A streptococcal M protein have been implicated in the pathogenesis of rheumatic heart disease. Although cardiac myosin is known to produce myocarditis in susceptible animals, it has never been investigated for its role in production of valvular heart...

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Main Authors: Galvin, Jeffrey E., Hemric, Mark E., Kosanke, Stanley D., Factor, Stephen M., Quinn, Anthony, Cunningham, Madeleine W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867128/
https://ncbi.nlm.nih.gov/pubmed/11786423
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