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Induction of Myocarditis and Valvulitis in Lewis Rats by Different Epitopes of Cardiac Myosin and Its Implications in Rheumatic Carditis

Immune responses against cardiac myosin and group A streptococcal M protein have been implicated in the pathogenesis of rheumatic heart disease. Although cardiac myosin is known to produce myocarditis in susceptible animals, it has never been investigated for its role in production of valvular heart...

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Detalhes bibliográficos
Main Authors: Galvin, Jeffrey E., Hemric, Mark E., Kosanke, Stanley D., Factor, Stephen M., Quinn, Anthony, Cunningham, Madeleine W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867128/
https://ncbi.nlm.nih.gov/pubmed/11786423
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