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Identification of Streptococcal M-Protein Cardiopathogenic Epitopes in Experimental Autoimmune Valvulitis

The M protein of rheumatogenic group A streptococci induces carditis and valvulitis in Lewis rats and may play a role in pathogenesis of rheumatic heart disease. To identify epitopes of M5 protein that produce valvulitis, synthetic peptides spanning A, B, and C repeat regions contained within the ex...

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Détails bibliographiques
Auteurs principaux: Kirvan, Christine A., Galvin, Jeffrey E., Hilt, Silvia, Kosanke, Stanley, Cunningham, Madeleine W.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943786/
https://ncbi.nlm.nih.gov/pubmed/24346820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-013-9526-4
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