MYCN Gene Amplification : Identification of Cell Populations Containing Double Minutes and Homogeneously Staining Regions in Neuroblastoma Tumors

Neuroblastoma is the second most common solid tumor occurring in children. Amplification of the MYCN oncogene is associated with poor prognosis. To identify neuroblastoma tumors with MYCN amplification, we studied the number of copies of MYCN in interphase cells by fluorescence in situ hybridization...

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Autors principals: Yoshimoto, Maisa, Caminada de Toledo, Silvia Regina, Monteiro Caran, Eliana Maria, de Seixas, Maria Teresa, de Martino Lee, Maria Lucia, de Campos Vieira Abib, Simone, Vianna, Sonia Maria Rossi, Schettini, Sergio Thomaz, Anderson Duffles Andrade, Joyce
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 1999
Matèries:
Short Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866968/
https://ncbi.nlm.nih.gov/pubmed/10550298
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