MYCN Gene Amplification : Identification of Cell Populations Containing Double Minutes and Homogeneously Staining Regions in Neuroblastoma Tumors

Neuroblastoma is the second most common solid tumor occurring in children. Amplification of the MYCN oncogene is associated with poor prognosis. To identify neuroblastoma tumors with MYCN amplification, we studied the number of copies of MYCN in interphase cells by fluorescence in situ hybridization...

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Detalhes bibliográficos
Main Authors: Yoshimoto, Maisa, Caminada de Toledo, Silvia Regina, Monteiro Caran, Eliana Maria, de Seixas, Maria Teresa, de Martino Lee, Maria Lucia, de Campos Vieira Abib, Simone, Vianna, Sonia Maria Rossi, Schettini, Sergio Thomaz, Anderson Duffles Andrade, Joyce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866968/
https://ncbi.nlm.nih.gov/pubmed/10550298
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