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Hibernomas are Characterized by Homozygous Deletions in the Multiple Endocrine Neoplasia Type I Region : Metaphase Fluorescence in Situ Hybridization Reveals Complex Rearrangements Not Detected by Conventional Cytogenetics

Hibernomas are benign tumors of brown fat, frequently characterized by aberrations of chromosome band 11q13. In this study, the chromosome 11 changes in five hibernomas were analyzed in detail by metaphase fluorescence in situ hybridization. In all cases, complex rearrangements leading to loss of ch...

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Autores principales: Gisselsson, David, Höglund, Mattias, Mertens, Fredrik, Dal Cin, Paola, Mandahl, Nils
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866650/
https://ncbi.nlm.nih.gov/pubmed/10393837
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