In Vivo Transfer of Interleukin-1 Receptor Antagonist Gene in Osteoarthritic Rabbit Knee Joints : Prevention of Osteoarthritis Progression

The goal of this study was to determine the efficacy of local IL-1Ra gene therapy by intra-articular plasmid injections on structural changes in the meniscectomy rabbit model of osteoarthritis. A partial meniscectomy of the right knee was performed on the rabbits through a medial parapatellar incisi...

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Main Authors: Fernandes, Julio, Tardif, Ginette, Martel-Pelletier, Johanne, Lascau-Coman, Viorica, Dupuis, Martine, Moldovan, Florina, Sheppard, Mike, Krishnan, B. Rajendra, Pelletier, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866546/
https://ncbi.nlm.nih.gov/pubmed/10233854
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